Expertin
Dr. Cécile Dumas

Expertise

Chemie: Synthesis of carbohydrate derivatives. Protection, deprotection reactions. Peptide coupling. Analyses and purifications of organic compounds: NMR, IR, HPLC, Mass, chromatography.

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Ausbildung

Universität
Chemie

Zusatzausbildung(en)
expertise in radioprotection

Weitere Fachrichtungen, weitere Ausbildungen
Organic chemistry Radiopharmacy

Sprachen

  • Französisch
  • Deutsch
  • Englisch
  • Italienisch
Mehr Details
  • Französisch

    Schriftlich: Muttersprache / wie Muttersprache
    Konversation: Muttersprache / wie Muttersprache

  • Deutsch

    Schriftlich: Grundkenntnisse
    Konversation: Gute Kenntnisse

  • Englisch

    Schriftlich: Gute Kenntnisse
    Konversation: Verhandlungssicher / Fließend

  • Italienisch

    Schriftlich: Grundkenntnisse
    Konversation: Verhandlungssicher / Fließend

Referenzen

Publikationen

1. Formation of Optically-Active 3-Hydroxypiperidines; Cossy, Dumas, Michel and Pardo; Tetrahedron Lett.; 1995; 36; 549-52.
2. Synthesis of (-)-pseudoconhydrine through ring enlargement of a L-proline derivative; Cossy, Dumas and Pardo; Synlett; 1997; 905.
3. A short and efficient synthesis of zamifenacin a muscarinic M-3 receptor antagonist; Cossy, Dumas and Pardo; Bioorg. Med. Chem. Lett.; 1997; 7; 1343-4.
4. Ring expansion - Formation of optically active 3-hydroxypiperidines from pyrrolidinemethanol derivatives; Cossy, Dumas and Pardo; Eur. J. Org. Chem.; 1999; 1693-9.
5. Functionalization of Glucose for the labeling with 99m-Tc Tricarbonyl; Dumas, Petrig, Schibli, Stahel, Schubiger, Spadola, Scapozza and Mertens; J. Labelled Cpd. Radiopharm.; 2001; 44; S57.
6. Derivatization of glucose and 2-deoxyglucose for transition metal complexation: Substitution reactions with organometallic Tc-99m and Re precursors and fundamental NMR investigations; Petrig, Schibli, Dumas, Alberto and Schubiger; Chem.-Eur. J.; 2001; 7; 1868-73.
7. Versatile routes to C-2- and C-6-functionalized glucose derivatives of iminodiacetic acid; Dumas, Schibli and Schubiger; J. Org. Chem.; 2003; 68; 512-8.
8. First Organo metallic inhibitors for human thymidine kinase: Synthesis and in vitro evaluation of Rhenium(I)- and Technetium(I)-tricarbonyl complexes of Thymidine; Schibli, Netter, Scapozza, Birringer, Schelling, Dumas, Schoch and Schubiger; Journal of Organometallic Chemistry; 2003; 668; 67-74.
9. Versatile synthetic approach to new bifunctional chelating agents tailor made for labeling with the fac-[M(CO)3]+ core (M = Tc, 99mTc, Re): synthesis, in vitro, and in vivo behavior of the model complex [M(APPA)(CO)3] (appa = [(5-amino-pentyl)-pyridin-2-yl-methyl-amino]-acetic acid); Stichelberger, Waibel, Dumas, Schubiger and Schibli; Nuclear Medicine and Biology; 2003; 30; 465-
70.
10. Novel organo-rhenium complexes with carbohydrate skeletons: Functionalization of glucose at postion C-3 for tranisition metal coordination; Dumas, Petrig, Spingler, Schubiger and Schibli; Journal of the American Chemical Society; submitted.

Cécile Dumas
Dr. Cécile Dumas

Paul Scherrer Institut

Kontakt

Letzte Aktualisierung: 05.05.2023